Questionnaire/history: Ocular discomfort increasing to pain? Lacrimation? Red eye? Photophobia? Contact lens wearer? Past medical history? Current medication? Drug allergies? Examination: Ulcer (stromal infiltrate with overlying epithelial loss) which may be round or arcuate, single or multiple, unilateral or bilateral, adjacent to limbus, and separated from limbus by interval of clear cornea? Ulcer stains with fluorescein? Hyperaemia and oedema of adjacent bulbar conjunctiva? Management: Ocular lubricants for symptomatic relief (drops for use during the day, ointment for use at bedtime) Paracetamol (+/- ibuprofen) for pain relief Referred to ophthalmologist (immediately if contact lens related) Moxifloxacin 0.5% eye drops as topical antibiotic treatment Reference(s): Patient UK: Corneal Problems - Acute and Non-acute The College of Optometrists: Keratitis (marginal) Information for patient/carer(s): American Academy of Ophthalmology: What Is a Corneal Ulcer (Keratitis)?